Is Skin Irritation of Topical Antifungal Agents Improved?

Recent advances in topical formulation carriers of antifungal agents.

Fungal infections are amongst the most commonly encountered diseases affecting the skin. Treatment approaches include both topical and oral antifungal agents. The topical route is generally preferred due to the possible side effects of oral medication. Advances in the field of formulation may soon render outdated conventional products such as creams, ointments and gels. Several carrier systems ...

Skin irritation and corrosion.

Khaki Drill and Skin Irritation

Sir,?The following facts may possibly be of interest to your readers and of use in cases similar to my own. For several years I suffered from an irritating skin disease which, without pathological examination of scrapings, was diagnosed variously as " tinea" or "lichen." Various doctors prescribed various ointments ?chrysarobin, benzoic, resorcin, salicylic, etc., etc., and iodine liniment, all...

Subgroup 2 . Skin Irritation / Corrosion

ECVAM, Institute for Health & Consumer Protection, European Commission Joint Research Centre, 21020 Ispra (VA), Italy; EVIC FRANCE,33290 Blanquefort, France; Syngenta, Central Toxicology Laboratory, Alderley Park, Macclesfield, Cheshire SK10 4TJ, UK; SEAC, Unilever Colworth Laboratory, Sharnbrook Bedfordshire MK44 1LQ,,UK; ZEBET BfR, Diedersdorfer Weg 1, 12277 Berlin, Germany; TNO Nutrition & F...

Efinaconazole 10% solution: a new topical treatment for onychomycosis: contact sensitization and skin irritation potential.

BACKGROUND Onychomycosis is a chronic condition that often requires long-term management to eradicate the causative fungus, allow a healthy nail to grow, and prevent relapse. As a successful outcome depends highly on patient adherence with treatment, a low risk of periungual skin irritation with topical medication is clinically relevant. OBJECTIVES To study the potential for efinaconazole 10%...